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In STEP 4, the extension of the STEP 1 trial of semaglutide, placebo patients regained around half their prior weight after a year

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MT-2 is used in rodent models to quantify hypophagia, fat-mass changes, and downstream metabolic readouts under different dietary contexts

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21 Since their recent increase in popularity and approval for use in some pediatric patients, more concerns have arisen regarding their effects on growth and development, mental health, and possible long-term consequences

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