effectiveness of tirzepatide vs semaglutide Semaglutide: Which Weight Loss Drug Is Best Semaglutide vs. Tirzepatide for Weight

Semaglutide (STEP 1 trial): Participants lost an average of 14.9% of body weight over 68 weeks at the 2.4 mg dose, compared to 2.4% with placebo

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A healthy weight loss is between 1-3 pounds per week, which means ideally you should lose between 4-12 pounds in a month on semaglutide, we aim for our patients to stay within this range

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Last accessed: May 2025

This is notably higher than what is typically observed with other weight loss interventions Appetite Control: Semaglutide works by mimicking the action of the hormone GLP-1 (glucagon-like peptide-1), which plays a role in regulating appetite