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The targets for Zn-mediated impact on energy metabolism may include PPARs (proliferator-activated receptors), which are responsible for the expression of mRNA genes that play a critical role in energy metabolism [98, 99]

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G6PD-d stimulates VECs to upregulate expression of chemoattractants and leukocyte adhesion molecules that could drive T cell recruitment to plaques 28,29,115

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