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10.1073/pnas.89.5.1567 29

It is a naturally-occurring tripeptide of the amino acids L-cysteine, Lglutamate and L-glycine that confers antioxidant assistance and promotes phase I conjugation pathways in the liver to support detoxification

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Conversely, when transsulfuration is stressed, methylation capacity may also be affected

Nalbandian, A., Desai, A

This work was supported by the Wilmot Cancer Institute Predoctoral Fellowship (G.A.), Wilmot Cancer Institute Pilot Funding (I.S.H.), the American Association for Cancer Research and Breast Cancer Research Foundation (20-20-26-HARR) (I.S.H.), Breast Cancer Coalition of Rochester (I.S.H.), a Sir Henry Wellcome Postdoctoral Fellowship (M.E.K.), and a FNR-CORE grant C21/BM/15796788 (D.B.), and NIH grants R01CA269813 (I.S.H.), R37CA230042 (G.M.D), R24AA022057 (V.V.), R01AA028859 (Y.C.), AI150698 (J.M.), K01CA240533-01A1 (C.L.C.), and R01AR078000 (R.T.D.)