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Due to the lack of effective therapy for fibromyalgia, many treatments are sought to reduce pain and fatigue and improve patients' quality of life

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Thomas Gates, then McNeils medical director, shot off a memo to the chief executive of Johnson & Johnson, the president of McNeil and other top officials, laying out a detailed plan of action for diffusing media interest in the research and limiting the extent and duration of the coverage. Gates envisioned two possibilities: Low Level of Publicity (most probable scenario) and High Level of Publicity (worst case scenario). For the latter, Gates suggested a series of responses: a letter-writing campaign to medical societies, doctors, pharmacists and academics

The antioxidant liquid (AOL) formulation and omega-3 based supplement containing Eicosatetraenoic acid (EPA), Docosahexaenoic acid (DHA), astaxanthin, and tocotrienols is likely responsible for this outcome

"Tranexamic acid slows melanin synthesis by inhibiting the plasminogen/plasmin pathway," says Hadley King, MD, a board-certified dermatologist based in New York City