Science 323, 101106 (2009)
As individuals age, there is an increase in pathogenic and putrefactive bacteria (e.g., Proteus ), while helpful bacteria such as Lactobacillus and Bifidobacterium diminish
A genetic test known as thiopurine methyltransferase (TMPT) genotyping can help predict who will have severe adverse effects from these drugs (Newman 2011)
MTHFR reductase deficiency is a common genetic mutation resulting in higher levels of the amino acid homocysteine in the blood and low levels of folate and cobalamin
If you want to see the formula built around that idea, start with Liposomal Glutathione
(And while you're at it, you might as well check in with your doctor to talk about which supplements, and in which dosages, you should be taking.)