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The evidence supporting GLP-1 medications for weight loss and metabolic health is robust

Reduced waist circumference by 3 1/2 inches 4.5 reduction in body-mass index 5 mmHg drop in Systolic BP Better physical functioning Improved lipid profiles: lower total cholesterol, VLDL and free fatty acids

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It reduces oxidative stress and inflammation, major contributors to heart disease

When nitric oxide production increases, blood flow improves, allowing nutrients and oxygen to replenish muscle tissue more efficiently

have found that progenitor cell division is enhanced after injected subcutaneously GLP-1 agonists exenatide (exendin-4) and liraglutide in the dentate gyrus of brain of mouse models of AD (166)