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The thymus is located above the heart, behind the collar bone, and in babies, it can be quite large, similar to the size of a baseball, but it significantly decreases in size with age, becoming mostly fat with small globules of thymic residue 4m30s

doi: 10.1016/j.celrep.2017.07.055 58 TarangeloAMagtanongLBieging-RolettKTLiYYeJAttardiLDet al

Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 19902021: a systematic analysis for the global burden of disease study 2021

J Neurosci Res 88(4):905916

Published clinical trials used continuous daily administration for 12-24 weeks without scheduled breaks, establishing this as a viable approach with maintained safety throughout the treatment period