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4.1 Immune imbalance Immune imbalance is the key amplifier that converts dysbiosis and epithelial stress into sustained inflammatory signaling, which subsequently perturbs iron regulation and favors ferroptosis-prone states

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On the neurological side, the pro-inflammatory factor released by AT may have first caused ferroptosis in the vagus nerve by inhibiting of the NRF2-GPX4 pathway, resulting in disorders of the autonomic nervous system

Women using oral contraceptives should discuss potential interactions and contraception planning