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Description

NF-B, Nuclear Factor kappa-light-chain-enhancer of activated B cells

Under normal conditions, Nrf2 is anchored in the cell cytoplasm by a repressor protein called Keap1

The World Health Organization (WHO)

For instance, a study demonstrated that blocking MCU significantly reduced ROS production and mitochondrial swelling in iron-overloaded thalassemic mice, suggesting that MCU could be a therapeutic target for preventing mitochondrial dysfunction in IOC (41, 89)