Prade, L., Huber, R., Manoharan, T.H., Fahl, W.E., Reuter, W
That is not a great combination
Intracellular GSSG was marginally decreased by KD of ALOX15 ( P = 0.069), but not by chemical inhibition ( P = 0.203
Animal studies show that gadolinium can cause low glutathione levels.[ref] Mercury is another heavy metal that utilizes glutathione in the detoxification pathways.[ref] Arsenic exposure causes increased glutathione usage
Nrf2 activators SFN and CDDO inhibit ferroptosis by activating the Nrf2 pathway To further elucidate how HT-induced ferroptosis works in colorectal cancer cells, two Nrf2 activators, SFN and CDDO, were employed
Under replete conditions, GCLC ligates glutamate to cysteine in the first step of glutathione synthesis