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Since then additional specific examples have been revealed, such as cleavage of the translation initiation factors eIF4F and eIF3 that leads to assembly inhibition of the of the pre-initiation complex (Baugh and Pilipenko, 2004) and cleavage of the tumor suppressor p53 precisely at position 40, generating the dominant negative 40p53 isoform (Solomon et al, 2017)

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