No regulatory body has cleared this formulation for any health application
Whether the early response after incision is mechanical sensitization remains controversial
Intraocularpressure in Lewis Rats
In scientific literature, NNMT is recognized as an enzyme that methylates nicotinamide (a precursor of NAD+) using S-adenosylmethionine (SAM) as the methyl donor, converting it to 1-methylnicotinamide (MNA) and potentially affecting cellular NAD+ availability
The Mayo Clinic indicates high doses of vitamin B-12, such as those used to treat a deficiency, might cause: Headache Nausea and vomiting Diarrhea Fatigue or weakness Tingling sensation in hands and feet Healthline says: In very rare cases, some people can experience side effects caused by allergic reactions or sensitivity In addition to helping athletes build muscle, vitamin B12 plays a role in maintaining nervous system function and brain health
They are slightly more expensive than "budget" vendors who don't provide COAs, but they are significantly more affordable than the legacy "medical-grade" research boutiques that charge a massive premium for their brand name