The S-alkyl moiety of the sulphoximine binds at the active site of the gamma-glutamyl cysteine synthetase that normally binds the acceptor amino acid [43, 44]
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In this paper, we review the literature on ferroptosis and its relationship with cancer from different perspectives, including proto-oncogene and tumor suppressor gene, epigenetics, cancer stem cells (CSCs), and the tumor microenvironment (TME)
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doi: 10.1093/ajcn/77.6.1352 49 BellIRMorrowFDReadMBerkesSPerroneG