Reactive astrocytes acquire neuroprotective as well as deleterious signatures in response to Tau and A pathology
The half-life time of TB-500 in rodents amounts to about two to three hours
Supplementing with NAC increases intracellular levels of glutathione, which is a super-antioxidant
GSH content was measured in a P96 automatic reader by the addition of 5,5 dithio- bis -2-nitrobenzoic acid (0.6 mM), NADPH (0.2 mM), and glutathione reductase (1 U), and the reaction was monitored at 412 nm for 6 min
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10.1007/s00228-012-1410-7 30 JamesL