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MT1 provides the receptor-activation benchmark against which pathway inhibition is measured

(7) D E Beck, W B Sweeney, and M D McCarter (2014) Prospective, randomized, controlled, proof-of-concept study of the Ghrelin mimetic ipamorelin for the management of postoperative ileus in bowel resection patients International Journal of Colorectal Disease, 2014 Dec, Volume 29 (Issue 12), Pages 1527-34

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The mice in the sham group underwent surgery involving kidney exposure without ligation

[371] Given the limited applicability of the trials' exclusion criteria to many RP patients, it's unlikely that future trials will include such individuals