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Peak antibody production is associated with increased oxidative metabolism in an industrially relevant fed-batch CHO cell culture

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Significant pathways identified included neutrophil degranulation, Innate Immune System, platelets degranulation, defects in vitamin and co-factor metabolism, activation of C3 and C5, attenuation phase and cellular response to heat stress (Figure 1)

Study authors consider it a potential tool in the management of high cholesterol and associated metabolic disorders

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