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10.3389/fneur.2015.00178 Front

The integration of real-time data can help in adjusting dosages as a patient's condition evolves, ensuring continuous optimization of therapy

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Activation of AMP-activated protein kinase by metformin improves left ventricular function and survival in heart failure

Among these, the IN route has gained increasing attention as a promising tool to bypass the BBB and deliver therapeutics (including iron chelators) directly to the CNS (Crowe and Hsu, 2022)

Bevacizumab was the first anti-angiogenic drug used in patients with RCC, followed by VEGFR inhibitors such as sunitinib, sorafenib, pazopanib, cabozantinib, and axitinib (101)