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For severe B12 deficiency that maybe causing significant neurological symptoms, your doctor may use injectable form of B12 initially before transitioning to oral therapy

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In the first step, the -glutamyl transpeptidase catalyzes the transfer of gamma-glutamyl functional groups from GSH to the cysteinylglycine dipeptide, which is subsequently convert to cysteine and glycine by a cysteinylglycine dipeptidase

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Some particularly stable peptides retain activity for even longer periods