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Herkmmliches Glutathion zeigt eine sehr schlechte Stabilitt und Bioverfgbarkeit, da es von Enzymen im Magen-Darmtrakt zersetzt wird und die Zellen zum Groteil nie erreicht

Absolute contraindications include known hypersensitivity or allergy to glutathione or any formulation components

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With the progress of clinical trials such as KEYNOTE-426, the combined use of immune checkpoint and protein tyrosine kinase inhibitors is now one of the standard treatment options for most patients with metastatic RCC (150)