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Nuclear factor-kappa B (NF-B) is a transcription factor that binds DNA and induces the transcription of the COX-2 gene, other pro-inflammatory genes, as well as genes involved in cell proliferation, adhesion, survival, and differentiation

Glutathione is a tripeptide composed of three amino acids: glutamine, glycine, and cysteine

In vivo, arctigenin (0.4 mg/mouse per day) reduced peanut sIgE and histamine levels and also blocked hypothermia in a PNA murine model [76]

Some scholars have proven that it can reverse the hypomethylation of genes [9] and attenuate oxidative stress and inflammation [10]