In PD, -syn aggregates deposit in oligodendrocytes, impairing myelination and disrupting axonal energy metabolism (e.g., via lactate supply disruption), exacerbating autophagy inhibition and necrosis [270]
Gli studi su animali non sempre rilevano effetti avversi sottili o a lungo termine che potrebbero manifestarsi nell'uomo
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Prolonged esophagitis after primary dysfunction of the pyloric sphincter in the rat and therapeutic potential of the gastric pentadecapeptide BPC 157
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