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Clinical spectrum and diagnostic pitfalls of neurologic syndromes with Ri antibodies

To minimize risks, consider the following precautions: Start with the lowest effective dose

2022;153 doi: 10.1016/j.neuint.2021.105268

Inflammation remains for too long

The reasons are multifaceted: rodent models of neurodegeneration imperfectly recapitulate human disease

For example, glucose is the main substrate that photoreceptors utilize to create ATP in vivo 12 , but they can oxidize lipids, lactate, and use amino acids, fatty acids (such as palmitate) and other intermediate substrates to produce ATP, especially under glucose-deprived conditions 10,11,12