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Subcutaneous injection (into fat tissue) is commonly used for amounts less than 0.5 mL
If mishandled, it should be handled only in qualified research facilities with institutional biosafety oversight
Oral LT4 is absorbed primarily in the small intestine, particularly in the jejunum and ileum, after dissolution in the stomach
17: Sikiric P, Boban Blagaic A, Krezic I, Zizek H, Kalogjera L, Smoday IM, Vukovic V, Oroz K, Chiddenton HM, Buric S, Antunovic M, Gojkovic S, Strbe S, Skocic M, Sikiric S, Milavic M, Beketic Oreskovic L, Kokot A, Koprivanac A, Dobric I, Sever M, Staresinic M, Batelja Vuletic L, Skrtic A, Seiwerth S
It has been used in clinical neurology for years, with an established safety profile and well-documented mechanisms of action
PMCID: PMC12944561
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