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3 In the past, liver transplantation had been the only therapeutic option for LAL-D because liver fibrosis progression was refractory to statin therapy

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Systemic testosterone is taken up by the muscle through its binding to membrane-bound or cytoplasmic androgen receptors (AR), in turn stimulating subsequent myocellular signaling (Vingren et al., 2010

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For example, IAV or SARS-CoV-2-induced NOX2 activity may suppress the TLR7-dependent antiviral response, thereby enhancing viral replication and pathogenicity 42,155

doi: 10.3390/diagnostics15010021