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When to stay at the starting dose longer There are valid reasons to remain at the starting dose beyond the standard four weeks

Baseline WOMAC pain score: approximately 6 out of 20 Reduction in active treatment arms: approximately 4.5 points , representing a ~76% decrease from baseline Complete freedom from knee pain at week 68: reported by roughly 1 in 8 patients (12.5%) receiving retatrutide, compared to just 4.2% in the placebo group A 76% reduction in pain scores is extraordinary approaching the range typically seen after total knee replacement surgery

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Peptides should be stored in a refrigerator (2C to 8C) after reconstitution

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CagriSema combines cagrilintide (an amylin analog) with semaglutide