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Mitochondria are eliminated at the stage of erythroblasts and reticulocytes via either macroautophagy (together with other organelles) or mitophagy, which is a more selective process [55]
doi: 10.1101/gad.17420111
Of Clin
The product is likewise indicated for increased physiologic demand (pregnancy, thyrotoxicosis, chronic hemorrhage), for drug-induced depletion, and for select neurologic or hematologic disorders in which B12 plays a pivotal metabolic role
Clinical trials reported no serious adverse events, with mostly mild to moderate side effects such as headache, dry mouth, and insomnia
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