Avoid sustained temperatures above 25C
But in practice, and especially with regard to synthetic and recombinant peptide forms, there are some considerable potential safety concerns: Immunogenicity Most notably, per a 2020 assessment on therapeutic peptide safety, synthetic and recombinant peptides pose the risk of immunogenicity the ability of a substance to provoke an immune response.15 An immunogenicity-inducing peptide, when introduced to the body, would cause the bodys immune system to perceive the peptide not as a medication but as a threat
You can learn more about this approach in Why Bioavailability Matters
Selectivity validation using GSH-depleted controls (e.g., buthionine sulfoximine [BSO]-treated cells) is a standard practice in well-designed preclinical studies
So, it's important for the immune system, for nervous function, and cognitive function as well
Discontinue use if irritation persists