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Additional information Statement of Financial Support This study was enabled by funding from the Netherlands Organisation for Health Research and Development ZonMw (Grant number: 80-83600-98-10190)

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Cleveland Clinics health articles are based on evidence-backed information and review by medical professionals to ensure accuracy, reliability and up-to-date clinical standards

In the skin, collagen serves as the primary structural component, providing the framework that maintains firmness, elasticity, and smoothness

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