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Neuropharmacology 167:107734

Additionally, catalpol activates the Osteopontin/phosphorylation-insulin-like growth factor 1 receptor (p-IGFR)/mTOR signaling axis, promoting the vitality, migration, and axonal growth of SH-SY5Y cells following OGD/reoxygenation injury, contributing to neuronal protection, nerve cell migration, and axonal regeneration under ischemic and hypoxic conditions ( Catalpol effectively alleviates cognitive impairment and neuropathological damage in isoflurane-exposed aged mice, showcasing its neuroprotective effects (Shi et al., 2022)

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Novel cAMP binding protein-BP (CREBBP) mutation in a girl with Rubinstein-Taybi syndrome, GH deficiency, Arnold Chiari malformation and pituitary hypoplasia