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One of the first accounts of cardiac regeneration in adult newt ventricle post-injury was published in 1974 by John and Jean Oberprillar 2

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Cells were then subjected to ROS level measurement using DCFH-DA probe, inflammatory cytokine detection using ELISA, and M1 polarization analysis using flow cytometry, as described above

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Tirzepatide, on the other hand, is unique because it acts on two hormones GLP-1 (like Semaglutide) and GIP (glucose-dependent insulinotropic polypeptide)