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KD metabolism produces ketone bodies, with BHB activating mitochondrial uncoupling protein-2 (UCP-2), helping modulate inflammation and metabolism [136]

16 Through both proactive and ongoing individualized therapy, pharmacists play a central role in mitigating and preventing the GI AEs associated with GLP-1 RA therapy

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Energy expenditure and fat oxidation rates were measured by indirect calorimetry at rest and during a cycle ergometer ramp exercise test (increments of 25 W every 3 min) until voluntary fatigue