If the cost of Wegovy is too high, there may be more affordable alternatives that could work for you
However, some studies suggest that thigh injections may result in slightly fewer gastrointestinal side effects for some individuals compared to abdominal injections
These skin reactions, which can include changes in facial skin condition, are considered less common than gastrointestinal side effects
The current evidence base for GLP-1 receptor agonist therapy is derived from extensive clinical trial programmes that have established the efficacy and safety of specific, licensed doses
However, consuming too few calories can lead to nutritional deficiencies, muscle loss, and fatigue, whilst excessive intake may limit therapeutic benefits
For example, in the LEADER trial, when compared with placebo, liraglutide decreased the incidence of major cardiovascular events (MACE) by 13%, cardiovascular death by 22% and all-cause death by 15% among T2DM patients with CVD, on a standard treatment basis [4]