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Additionally, BACH1 disappeared at a slower rate in HUVECs after protein synthesis was inhibited with CHX (Fig

Hollman G, Kristenson M

Mammalian genome: official journal of the International Mammalian Genome Society

In MOGAD it may be caused by direct destruction of myelin by anti-MOG autoantibodies-induced autoimmune reaction

So while the short-term pelvic floor changes are real, the long-term trajectory for many people with obesity-related incontinence may actually be improvement