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One unit per kilogram body weight will raise the factor VIII level by 2% international units per deciliter (IU per dL)

2011;34(suppl 1):S62-S69

Kirsch et al., 2016

The triagonist IUB447 has shown superior efficacy compared with existing dual co-agonists and best-in-class mono-agonists in reducing body weight and improving glycaemic management in relevant rodent models