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Failure to use the product strictly as directed may be illegal, dangerous and render the product ineffective Questions and answers from customers Is it safe to vax cows in their 3rd trimester Q Is it safe to vax cows in their 3rd trimester Asked by Sheran on January 17, 2022 2:45 pm Answered by the admin The Cobalex 2000 B12 Injection is safe to use on cattle late into pregnancy