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J Nanobiotechnol 20(1):362

A study published in the Proceedings of the National Academy of Sciences found that aging is associated with a 47% decrease in the catalytic subunit (GCLC) and a 52% decrease in the modulatory subunit (GCLM) of glutamate-cysteine ligase, the rate-limiting enzyme for glutathione production

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Trends Cell Biol 2018;28:201-12

51 Developmental and Early-Life Exposures Some evidence suggests that certain exposures can affect the development of fetal and immature ovaries