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Molecular mechanisms underlying bile acid-stimulated glucagon-like peptide-1 secretion

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It is indicated for people with positive SARS-CoV-2 tests who are at high risk for progressing to severe COVID-19

The clinical experts also noted that patient registries for BBS would be of great value because there are still evidence gaps, especially regarding long-term efficacy and safety, given that obesity is a chronic, long-term, relapsing condition

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47 Visceral fat accumulation in patients with obesity causes a number of changes (oxidative stress, activation of the RAAS and gut dysbiosis), resulting in insulin resistance, increased vascular stiffness, T2D, dyslipidaemia, hypertension, coronary atherosclerosis and, ultimately, HFpEF