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7 However, increasing lipophilicity is not a universal strategy as it may inhibit the biological activity of drugs of interest

Sometimes the body uses L-Carnitine faster than it can be synthesized, at which point it is considered a conditionally essential nutrient

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Perry RJ, Samuel VT, Petersen KF, Shulman GI (2014) The role of hepatic lipids in hepatic insulin resistance and type 2 diabetes

In conclusion, there's no hard-set rule stamped in copper (peptides)