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Ask those questions of your provider before your first dose - they have straightforward answers

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Baseline: 2 to 3 litres daily Training days: Closer to 3.7 litres, depending on your activity level First thing in the morning: About 500ml within 30 minutes of waking up That morning, your body loses fluid overnight, and GLP-1 medication can make morning nausea worse on an empty, dehydrated stomach

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In vitro organoid studies: Murine and human intestinal organoids were used to study molecular mechanisms

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These tend to lessen as the body adjusts

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6 With their multiple effects on metabolism, GLP-1 RAs are also being investigated for obesity management as well as the treatment of neurodegenerative, cardiovascular, digestive, and musculoskeletal disorders

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