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A correlation has been found between BA metabolism and glomerulosclerosis and tubulointerstitial fibrosis in DKD (127, 128), possibly through the inhibition of ligand-activated nuclear receptor Farnesoid X Receptor(FXR)/retinoid X receptor activation, which is strongly associated with ferroptosis (129)
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Oocyte maturation interference independent of weight loss Preclinical studies suggest that glucagon-like peptide-1 receptor agonists may influence ovarian signaling, including granulosa cell pathways and intrafollicular growth factors such as IGF-1 and AMH, though direct human evidence is sparse [22]
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Older adults also deserve attention, as digestive changes associated with aging can make it harder to release and absorb the vitamin present in food
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