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While vials offer lower-cost options, pen devices provide ease of administration, which could influence patient preference and prescribing behaviour as the market develops

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Probiotics are defined as live microorganisms that confer health benefits to the host when administered in adequate amounts (FAO/WHO 2002)

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Statistical analysis The results were presented as risk ratios (RRs) for dichotomous variables and standardized mean differences (SMDs) for continuous variables, each with 95% confidence intervals (CIs)

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