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But for an endurance athlete trying to meet high energy demands and fuel long workouts or races, these same effects can become serious liabilities

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The mechanisms include endothelial dysfunction, autonomic neuropathy, reduced nitric oxide bioavailability, and psychological factors related to chronic disease management

Consider over-the-counter options if needed Occasionally, mild stool softeners, osmotic laxatives, or fiber supplements may help relieve constipation

Body weight management and safety with efpeglenatide in adults without diabetes: a phase II randomized study