Additionally, when the cells do not repair or regenerate the way they once did, the body has less natural help available to fix the signs of aging on its own
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These compositional shifts are accompanied by elevated levels of uremic toxins (IS, PCS, indole, and p-cresol) and secondary bile acids derived from aromatic amino acid degradation and microbial secondary bile acid biosynthesis ( Table 1 ) [110]
Figure13 shows the outcome for the 53 patients in the study of Remien et al.[10]