These findings suggest that GLP-1 receptor agonists may hold promise as therapeutic interventions for patients [18], [58]
Flor-Alemany M, Marin-Jimenez N, Coll-Risco I, Aranda P, Aparicio VA
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The effects of apoptosis stimulation were confirmed to occur only in cells expressing GLP-1R in a gain-of-function experiment ( 4.2 Hepatic metabolic modulation effects by GLP-1RAs GLP-1RAs replicate the action of the incretin hormone GLP-1, which primarily involves boosting insulin release, reducing glucagon secretion, and increasing feelings of fullness, ultimately leading to improved glycemic control and supporting weight management (Xu et al., 2024)