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61 Finally, the effector protein, typically a caspase enzyme, is recruited to the complex and activated, initiating downstream signaling events that lead to inflammation and cell death

Antioxidants & Redox Signaling 23 (17): 13161328

BMI: body mass index, HbA1c: glycated hemoglobin, FPG: fasting plasma glucose, CGM: continuous glucose monitoring

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228 SIRT1 is a direct target of Notch-Hes1, and Notch drives senescence of liver sinusoidal endothelial cells in a SIRT1-dependent manner

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