In metabolic conditions such as diabetes, prolonged hyperglycemia can damage small nerve fibers through multiple pathways including oxidative stress, accumulation of advanced glycation end products, and microvascular insufficiency affecting nerve blood supply
The mechanisms underlying these effects include modulation of the skin immune response by suppressing the production of inflammatory cytokines, such as interleukin (IL)-1 and tumor necrosis factor-alpha (TNF), and increasing the production of anti-inflammatory cytokines, such as IL-4 and IL-10, therefore promoting a favorable environment for tissue healing and reducing inflammation (Routley and Ashcroft, 2009
Koyuturk M, Bolkent S, Ozdil S, Arbak S, Yanardag R
Oct 2012;67(4):658-664
Adrenal Insufficiency
Protein helps increase satiety hormones, reduces blood sugar spikes after meals and supports muscle mass, which plays a key role in improving insulin sensitivity, she adds