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Importantly, these phenotypes contrast with the non-inducible liver-specific Gclc KO mouse strain ( Gclc f/f Albumin-Cre), which develops liver failure and dies shortly after birth 30

DIO = diet-induced obese

Figure 7 displays the results for the oxidative phosphorylation pathway, illustrating reduced expression of subunits belonging to NADH dehydrogenase (Complex I), succinate dehydrogenase (Complex II), cytochrome bc1 complex (Complex III), cytochrome c oxidase (Complex IV), and ATP synthase

Inflammation and its role in neuroprotection, axonal regeneration and functional recovery after spinal cord injury

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The trials enrolled people with obesity or type 2 diabetes who were trying to lose weight