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SB: Writing original draft, Supervision, Data curation

Retatrutide is an investigational triple agonist targeting GLP-1, GIP, and glucagon receptors, currently unapproved by the MHRA, EMA, or FDA for routine clinical use

Importantly, several studies have reported GLP-1R expression on both hepatocytes (liver cells) and adipocytes (fat cells) (Zhang et al., 2025

doi: 10.1016/j.jaad.2017.08.042

It is easy to assume that GSTT1 testing and liver function or general "detox" blood panels tell you the same story, but they answer different questions

It is unknown whether or not the patients included in the analysis maintained a healthy diet and exercise regimen, which can help mitigate bone density loss