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Expert opinion on investigational drugs, 2009, 18(12): 1893-1905

It delivers copper to the skin but lacks the peptide-mediated signaling activity of GHK-Cu

We now demonstrate that GIPR agonist administration critically relies on Gipr expression in the hindbrain, while GIPR antagonism relies on hypothalamic Gipr expressionboth are probably neuronal populations, given that we used hSyn-driven Cre-expression for the region-specific knockout studies

It's a naturalis a natural hydrator that can moisturize the skin without making it oily.

Artells et al

[3] Pal-GHK (palmitoyl-GHK) is a lipid-modified version of GHK designed for better skin penetration